The good news? These side effects are temporary and resolve once the steroid therapy is concluded. Many MS patients are given corticosteroids for MS relapses, either in intravenous ( Solu-Medrol, methylprednisolone) or oral form ( Deltasone, prednisone), over a period of three to seven days.Ĭommon side effects for either steroid treatment are insomnia at night and excessive daytime sleepiness. Ask your doctor or pharmacist for other options for managing this side effect. In some cases, a physician may suggest the use of Benadryl to counteract the intense itching that might accompany flushing. However, those taking certain disease-modifying therapies may experience a distinct "flushing" side effect. These medications (mostly diphenhydramine, which is found in Benadryl) are typically not recommended for people with MS because they can disrupt memory and learning. If sleeplessness is a recurring problem with these kinds of medications, a discussion with the prescribing physician might be in order, as reduced dosages might still be effective for those who are sensitive to them. This might seem obvious, but some people can take a drug like Provigil ( modafinil) or Nuvigil ( armodafinil) early in the morning (7am) in order to stay awake during the day and still experience its effects at 11pm that night.Īdderall, a stimulant medication ( amphetamine and dextroamphetamine), is also well known for causing insomnia or restless sleep, but may be used to counteract extreme daytime fatigue.Īmantadine ( Symmetrel) is an antiviral medication that can help with daytime fatigue, but be aware: if taken too late in the day, it can disrupt nighttime sleep. Taking a prescription for wakefulness may lead to a delay in sleep onset at night.
This medication can also cause diarrhea and irritable bowel symptoms that may intrude upon sleep. Tecfidera ( dimethyl fumarate) is known to cause flushing, which can occur in the middle of the night and lead to a raging neurological itch that lasts for around 20 minutes. Revia ( Low-dose naltrexone) is known to lead to sleep disturbances in its users. Rebif( interferon beta 1a) can also lead to sleepiness related to liver problems. Plegridy(peginterferon beta 1a) may lead to extreme sleepiness that is the result of liver problems which can be a side effect of this medication. Lemtrada( alemtuzumab) can cause some sleeping issues a few days following infusion. Copaxone( glatiramer acetate) has been shown to lead to overall poor sleep quality.Įxtavia( interferon beta 1b) is known to cause insomnia in some users.
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